Katherine Rose Birditt

PhD thesis: TBC

The project aims to investigate the brain imaging features of frontotemporal dementia and related disorders. By analysing multimodal brain imaging data and blood-based biomarkers, and integrating this information with clinical data, I aim to detect early brain changes that contribute to the rapid progression of the disorder. Specifically, my work will explore the interactions between inflammation, genetic markers, and metabolomics to enhance our understanding of how these parameters associate with one another and evolve over the course of the disease. The goal of this research is to gain deeper insights into the mechanisms underlying frontotemporal dementia, thereby improving its diagnosis, aiding in prognostic monitoring, and hopefully informing the development of more effective therapeutic strategies.

Who or what inspired you to pursue your research interests?

Having volunteered within the Zimbabwean neurological healthcare sector, I came to realise that dementia was an impending future problem for Africa. Immersed within a crumbling, overburdened healthcare system, the desire to revolutionise the landscape of dementia research, diagnosis and treatment across the continent was instilled within me. This aspiration transformed into a clearer vision as I pursued higher education in the UK. During research internships and projects, I was mentored by brilliant scientists who inspired, challenged and equipped me with a skillset that has empowered me to pursue research into an area I am so passionate about.